Like all medicines, Fioricet can have side effects.

Common Side Effects of Fioricet
Among the most commonly reported:

Drowsiness
Lightheadedness, dizziness
Feeling short of breath
Nausea, vomiting, stomach pain
Feeling of intoxication

Severe Side Effects of Fioricet

If you have any of the following symptoms, contact your doctor right away or go to the closest emergency room:

• Skin rash
• Itching
• Breathing problems

• Rare Side Effects of Fioricet

  Other side effects of Fioricet are infrequent. Among these are:

• Dry mouth, swallowing problems
• Gas, constipation, heartburn
• Leg pain or fatigued muscles
• Fever

SIDE EFFECTS

Frequently Observed

The most frequently reported adverse reactions are drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, and intoxicated feeling.

Infrequently Observed

All adverse events tabulated below are classified as infrequent.

Central Nervous System: headache, shaky feeling, tingling, agitation, fainting, fatigue, heavy eyelids, high energy, hot spells, numbness, sluggishness, seizure. Mental confusion, excitement or depression can also occur due to intolerance, particularly in elderly or debilitated patients, or due to overdosage of butalbital.

Autonomic Nervous System: dry mouth, hyperhidrosis.

Gastrointestinal: difficulty swallowing, heartburn, flatulence, constipation.

Cardiovascular: tachycardia.

Musculoskeletal: leg pain, muscle fatigue.

Genitourinary: diuresis.

Miscellaneous: pruritus, fever, earache, nasal congestion, tinnitus, euphoria, allergic reactions.

Several cases of dermatological reactions, including toxic epidermal necrolysis and erythema multiforme, have been reported.

The following adverse drug events may be borne in mind as potential effects of the components of this product. Potential effects of high dos age are listed in the OVERDOSAGE section.

Acetaminophen: allergic reactions, rash, thrombocytopenia, agranulocytosis.

Caffeine: cardiac stimulation, irritability, tremor, dependence, nephrotoxicity, hyperglycemia.

Drug Abuse And Dependence

Abuse And Dependee

Butalbital

Barbiturates may be habit-forming: Tolerance, psychological dependence, and physical dependence may occur especially following prolonged use of high doses of barbiturates.

The average daily dose for the barbiturate addict is usually about 1500 mg. As tolerance to barbiturates develops, the amount needed to maintain the same level of intoxication increases; tolerance to a fatal dosage, however, does not increase more than two-fold. As this occurs, the margin between an intoxication dosage and fatal dosage becomes smaller. The lethal dose of a barbiturate is far less if alcohol is also ingested.

Major withdrawal symptoms (convulsions anddelirium) may occur within 16 hours and last up to 5 days after abrupt cessation of these drugs. Intensity of withdrawal symptoms gradually declines over a period of approximately 15 days. Treatment of barbiturate dependence consists of cautious and gradual withdrawal of the drug.

Barbiturate-dependent patients can be withdrawn by using a number of different withdrawal regimens. One method involves initiating treatment at the patient’s regular dosage level and gradually decreasing the daily dosage as tolerated by the patient.

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Fioricet is available as tablets for oral administration, to be taken whole, by mouth, with or without food. The recommended dosage is of 1-2 tablets every 4 hours or as the doctor prescribes. Fioricet treatments can cause nausea and this is why most patients prefer to take this medication without food. Talking to the doctor about the nausea problem could lead to finding out essential information on how to reduce this unwanted effect. In fact, he/she can prescribe antihistamines for the nausea but there is also the possibility of lying down one hour after taking the medication.

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Fioricet is a combination medication commonly used to treat tension headaches but doctors also recommend it for recurring migraines. Acetaminophen is used to decrease the pain associated with muscular tension and caffeine increases the efficiency of the pain-killing effect. The last constituent of Fioricet is butalbital, a powerful sedative having the property to reduce anxiety and induce relaxation. This barbiturate is also responsible for the sleepiness appearing after Fioricet intake.

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